Table 5 HYPHEN progression criteria
HYPHEN progression criteria | Go—proceed to larger scale (RCT) | Amend—proceed with changes | Stop—do not proceed unless changes possible |
|---|---|---|---|
Feasibility of participant recruitment—can 30 participants be recruited in 1 week? | If 30 participants are recruited in 1 week (100%) | If 15 to 29 participants are recruited in 1 week (50 to < 100%) | If < 15 participants are recruited in 1 week (< 50%) |
Feasibility of patient retention—can at least 80% of recruited participants be retained until study end? | ≥ 24 (80%) retained | 21–24 (70–80%) retained | < 21 (70%) retained |
Feasibility of engagement—can at least 80% of recruited participants provide complete weekly data | ≥ 24 (80%) engaged | 21–24 (70–80%) engaged | < 21 (70%) engaged |
Feasibility of intervention implementation | Delivery of intervention judged strongly feasible by qualitative data | Delivery of intervention judged feasible by qualitative data | Delivery of intervention judged possibly feasible by qualitative data |