Table 5 Secondary measures

Sense of meaning

Personal Meaning Index of the Life Attitude Profile – Revised (LAP-R) [56]

16 items, 7-point Likert scale from 1 (strongly agree) to 7 (strongly disagree). Scores are summed

Quality of life

Functional Assessment of Chronic Illness Therapy – General (FACT-G) [57]

27 items, 5-point Likert scale from 0 (not at all) to 4 (extremely). Four subscales, summed

Spiritual well-being

Functional Assessment of Chronic Illness Therapy – Spiritual Well-being 12-item scale (FACIT-SP-12) [58]

12 items, 5-point Likert scale from 0 (not at all) to 4 (very much). Scores are summed

Sense of connectedness

Watts Connectedness Scale [59]

19 items, rated on VAS (0–100), anchors: ‘Not at all’ and ‘Entirely’. Three subscales, reported as mean scores and subscale means

Anxiety and depression

Depression, Anxiety and Stress Scale (DASS-21) [60]

21 items, 5-point Likert scale, from 0 (never) to 4 (almost always). Three subscales, reported as summed scores (each subscale sum multiplied by two)

Hospital Anxiety and Depression Scale (HADS) [61]

14 items, 5-point Likert scale (0–4). Two subscales, reported as summed scores

Te Whare Tapa Wha Mental Health outcomes

Hua Oranga [62]

14 items, 5-point Likert Scale (1–5). Four subscales, reported as subscale or total questionnaire summed scores

Demoralisation

Demoralization Scale [63]

24 items, 5-point Likert scale, ranging from 0 (never) to 4 (all the time). Five subscales, reported as summed scores

Attitudes towards death

Schedule of Attitudes towards Hastened Death (SAHD) [64]

20 items, scored 0 (false) or 1 (true), reported as a total sum

Personality

Big Five Inventory (BFI-2-XS) [65]

15 items, 5-point Likert scale, ranging from 1 (disagree strongly) to 5 (agree strongly). Five subscales, reported as summed scores

Therapeutic alliance

Working Alliance Inventory Short Form (WAI-SF) [66]

12 items, 5-point Likert scale, ranging from 1 (seldom) to 5 (always). Three subscales, reported as summed scores

Altered states of consciousness

5-Dimensional Altered States of Consciousness Rating Scale (5D-ASC) [67]

94 items, with 5 scales and 11 subscales reported as % of the maximum score

Personality: absorption

Modified Tellegen Absorption Scale (MODTAS) [68]

34 items rated on a 5-point scale (0–4) reported as the sum of scores (0–136)

Treatment expectancy

Treatment Expectancy Questionnaire [69]

15 items rated on an 11-point Likert scale

Pain

Brief Pain Inventory – Short Form (BPI-SF) [70]

4 severity items and 7 interference items, rated on an 11-point Likert scale, ranging from 0 (no pain/does not interfere) to 10 (pain as bad as you can imagine/completely interferes), the two subscales are reported as means

Measurement of blinding

Dose Day Questionnaire

Single-item measure (placebo, LSD, don’t know)

Subjective drug effects

Drug Effects Visual Analogue Scale [39]

12 items, rated on VAS (0–100), reported individually and as mean score

Caregiver stress – support person only

Kingston Caregiver Stress Scale [71]

10 items, rated on 5-point Likert scale, reported as the sum of scores (10–50)

Closeness to others – support person only

Inclusion of Other in Self [72]

Single-item measure, between 1 and 7