Wk0 | Wk2 | Wk4 | Wk6 | ||
---|---|---|---|---|---|
Patient information | Consent and patient demographics | X | |||
Medical history | X | ||||
Medications | X | X | X | X | |
Infection risk | X | ||||
Immunological risk | X | ||||
Transplant history | X | ||||
Transplant course specifically documenting infection events | X | X | X | ||
Standard care biochemistry | Full blood count Urea and electrolytes Fasting blood glucose HbA1c | X | X | X | X |
Uremic toxins | Total serum IS | X | X | ||
Free serum IS | X | X | |||
Total serum pCS | X | X | |||
Free serum pCS | X | X | |||
Gut microbiota | Bristol stool evaluation and stool sample collection | X | X | X | |
Inflammatory markers | C-reactive protein | X | X | ||
Quality of life (EQ-5D) | X | X | |||
Prebiotic dose commencement | X | X | |||
Prebiotic dose escalation | X | ||||
Gastrointestinal symptoms (GSRS) | X | X | X | ||
Compliance | Weight of powder | X | |||
Serious adverse events | X | X | X | ||
Adverse events | X | X | X |