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Table 1 Data collection schedule and parameters to be collected

From: PREBIOTIC: a study protocol of a randomised controlled trial to assess prebiotic supplementation in kidney transplant recipients for preventing infections and gastrointestinal upset — a feasibility study

 

Wk0

Wk2

Wk4

Wk6

Patient information

Consent and patient demographics

X

   

Medical history

X

   

Medications

X

X

X

X

Infection risk

X

   

Immunological risk

X

   

Transplant history

X

   

Transplant course specifically documenting infection events

 

X

X

X

Standard care biochemistry

Full blood count

Urea and electrolytes

Fasting blood glucose

HbA1c

X

X

X

X

Uremic toxins

Total serum IS

X

  

X

Free serum IS

X

  

X

Total serum pCS

X

  

X

Free serum pCS

X

  

X

Gut microbiota

Bristol stool evaluation and stool sample collection

X

X

 

X

Inflammatory markers

C-reactive protein

X

  

X

Quality of life (EQ-5D)

X

  

X

Prebiotic dose commencement

X

X

  

Prebiotic dose escalation

 

X

  

Gastrointestinal symptoms (GSRS)

X

X

 

X

Compliance

Weight of powder

   

X

Serious adverse events

 

X

X

X

Adverse events

 

X

X

X